Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf0f68bc9b66c444a1b7b970ce248f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09338f50511d9e40c2caa73805df5447 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-212 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
filingDate |
2004-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a3b248b28b34e0712a1f2ff9af890b0 |
publicationDate |
2005-02-17^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005013917-A2 |
titleOfInvention |
Combination therapy for treating alphavirus infection and liver fibrosis |
abstract |
The present invention provides methods for treating alphavirus infections; methods of treating hepatitis C virus (HCV) infections; methods of treating West Nile virus infection; methods of reducing liver fibrosis; methods of increasing liver function in an individual suffering from liver fibrosis; methods of reducing the incidence of complications associated with HCV and cirrhosis of the liver; and methods of reducing viral load, or reducing the time to viral clearance, or reducing morbidity or mortality in the clinical outcomes, in patients suffering from viral infection. The methods generally involve administering effective amounts of an interferon receptor agonist and pirfenidone in combination therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2294189-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8383823-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544161-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898474-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9504677-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10010536-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8969575-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8969576-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2123748-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233195-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9018232-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE47142-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9062001-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010065755-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8680123-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9675593-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10376497-B2 |
priorityDate |
2003-02-28^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |