http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006066240-A2

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filingDate 2005-12-19^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-06-22^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006066240-A2
titleOfInvention Methods for assessing patients with acute myeloid leukemia
abstract Methods for treating cancer, and preferably hematological malignancy, patients include analyzing gene expression profiles and/or molecular markers of a patient to determine status and/or prognosis of the patient. The invention also provides methods of analyzing whether a non-relapsed or non-refractory patient is likely to respond to treatment with farnesyl transferase inhibitors (FTIs) and, optionally, other therapeutics. The methods are also useful for monitoring patient therapy and for selecting a course of therapy. Genes modulated in response to FTI treatment are provided and are used in formulating the profiles.
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