| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21a431418f831f5e302080f20a0d8620
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9865da1ad7d772bc30d195119f481f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3107e9126d5db95e7316de4e729d4cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd9d5b8e54d5381f8486cfaa4d77e01f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6dc875920b3245b15d1846dac13513c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1db825b7ae0aa30215e2067dee758468 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 |
| filingDate |
2006-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54cd50ea7336f792a7616063293db6e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70a6a1762a0673b615030b3bea7704b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23606ed71fc971c7137adc6dac5843fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae64c52584b173be463c7236d13a031b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d91bda6a24b7f94136cf0bc4287f12b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d7d4199707a5d5be919bcb1719f0434 |
| publicationDate |
2007-04-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006127948-A3 |
| titleOfInvention |
N-terminally modified glp-1 receptor modulators |
| abstract |
The subject matter described herein provides novel human glucagon-like peptide-1 (GLP-1) receptor modulators that have biological activity similar or superior to native GLP-1 peptide and thus are useful for the treatment or prevention of diseases or disorders associated with GLP activity. The described compounds include chemically modified peptides that not only stimulate insulin secretion in type II diabetics, but also produce other beneficial insulinotropic responses. These synthetic peptide GLP-1 receptor modulators exhibit increased stability to proteolytic cleavage making them ideal therapeutic candidates for oral or parenteral administration. The disclosed and claimed peptides show desirable pharmacokinetic properties and desirable potency in efficacy models of diabetes. |
| priorityDate |
2005-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |