| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d7c126ccce89c7713cc7ff7d2634fde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1a88f6bb15049760ffc496fe9dc609b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676b80da7ac92b84e447a83fb1630ae1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4965 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 |
| filingDate |
2007-01-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71d1f21ac9fb75b5f9f743606be369fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e32fa3ed2a85d5572b512da7d9d56acc |
| publicationDate |
2007-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007084464-A2 |
| titleOfInvention |
Water channel blockers and methods of use thereof |
| abstract |
The present invention provides a method of blocking water channels (such as aquaporins) in a subject in need thereof, comprising administering to said subject an active compound to block water channels in said subject, as well as the use of an active compound for the preparation of a medicament for blocking water channels in a subject in need thereof. Active compounds include pyrazinoylguanidine compounds (e.g. amiloride, benzamil, phenamil) and pharmaceutically acceptable salts or prodrugs thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11071744-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11084778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10258636-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9827253-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9949991-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9994514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9573885-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10894055-B2 |
| priorityDate |
2006-01-17^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |