Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4a36c764cdd580a57c85108f1baaed5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e72837de81999e7e72cb78d59d19e28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4418e66aee654cfaf64463c3b4306b0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7de402678c1a1bed2289423d4068190d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
2007-04-23^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae2f7ca28e340965926857e296ace403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f48e2d9786712db52139c14622947c45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ea5546276900fe5abbf864c81f9b817 |
publicationDate |
2007-11-08^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007127151-A2 |
titleOfInvention |
Non-human model of autoimmune disease |
abstract |
The invention is directed to a method of producing a non-human mammal having one or more pathological characteristics of retinal degeneration and/or age- related macular degeneration. In particular, the invention provides a method of producing a non-human mammal having age-related macular degeneration (AMD). The invention is also directed to non-human animals produced by the methods described herein. Methods of identifying an agent for use in inhibiting one or more pathological characteristics of retinal degeneration and/or AMD is also encompassed by the invention. Also provided is a method of treating AMD in an individual in need thereof comprising, administering to the individual an agent identified herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010023539-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8137991-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8664470-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2161330-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010132459-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010132459-A2 |
priorityDate |
2006-04-24^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |