http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008082646-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7102a912faad1b9a1c56452bbf0db770
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-05
filingDate 2007-12-28^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef1afe2163802dcc92389b14feaf5d3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9405769b00887d21829dfba93ba2329
publicationDate 2008-07-10^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008082646-A2
titleOfInvention Histone deacetylase inhibitors, combination therapies and methods of use
abstract The invention relates to histone deacetylase (HDAC) inhibitors to treat proliferative diseases. The present invention provides novel class III histone deacetylase inhibitors, in particular SIRTl inhibitors, to reverse the silencing of hypermethylated genes, in combination with one or more other agents, in proliferative diseases such as cancer. The present invention provides methods of activating genes that are silenced by methylation in a subject by administering a HDAC inhibitor in combination with one or more agents.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012504112-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010034693-A1
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priorityDate 2006-12-28^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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