| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d8aa7c0c9d6c764b9c7e3ac192a96dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6063fbefd325c93a8f276e12a263a790
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04d6b82552df55a4893cf414e04bd26a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_189890e78f6f5e5945c6c0927577b184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c50f5cf69563da54bfa91a75d8d5e21f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| filingDate |
2008-01-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c9c56b31388a7ed336f4961feb2818e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9de3701670d728241a703b2be10c68c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4730deb5cf7e2a6adc35fe29e700d2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_470fdb09a0ddb1551b1d18cae2d7256e |
| publicationDate |
2008-07-24^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008087557-A2 |
| titleOfInvention |
An improved process for preparation of 9-hydroxy-3-(2-chloroethyl)- 2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one hydrochloride |
| abstract |
Described herein is an improved, commercially viable and industrially advantageous process for the preparation of paliperidone intermediate 9-hydroxy-3-(2-chloroethyl)-2- methyl-4h-pyrido[1,2-a]pyrimidin-4-one and its hydrochloride salt. The process provides the paliperidone intermediate in higher yield and reduced reaction time compared to the previously disclosed processes, thereby providing for production of paliperidone and its pharmaceutically acceptable acid addition salts in high purity and in high yield. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011030224-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011030224-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011073997-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7820816-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2202234-A1 |
| priorityDate |
2007-01-08^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |