abstract |
This application relates to methods for treating an aneurysm or an aortic dissection (230; 530). The methods include delivering a medical device (10; 100; 150; 200; 400) and a c-Jun N-terminal kinase (JNK) inhibitor compound to a body lumen at a point of treatment within a subject having the aneurysm or aortic dissection (230; 530), the medical device (10; 100; 150; 200; 400) being adapted to release the JNK inhibitor within the body lumen of the subject. This application also relates to medical devices (10; 100; 150; 200; 400) and JNK inhibitor compounds, where the medical device (10; 100; 150; 200; 400) is adapted to release the JNK inhibitor compound within a patient. Medical devices may include coated stents, grafts, stent grafts, balloons and catheters. |