| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e13e4c13fe64996895413453879610c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c1ed9172be30413aa370d8589890799
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a583ac8ac8f8c952847026833ecda0ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7bee24c10d58e60f4abd6a5ea5b0091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91e2cb26955bbd751109d3c35b48a395 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2008-02-29^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93dbab2be524740fa845df8e1486a0d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45f88e6c07c362faf66ff706dbc47764
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07971722a39ebdc3c84ae2498442c432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c74a5b34c8d64da50e938c245854ddc5 |
| publicationDate |
2009-02-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008109450-A9 |
| titleOfInvention |
Nucleic acid compounds for inhibiting id-1 gene expression and uses thereof |
| abstract |
The present disclosure provides meroduplex ribonucleic acid molecules (mdRNA) capable of decreasing or silencing ID-I gene expression. An mdRNA of this disclosure comprises at least three strands that combine to form at least two non-overlapping double-stranded regions separated by a nick or gap wherein one strand is complementary to an ID-I mRNA. In addition, the meroduplex may have at least one uridine is a 5-methyluridine, a nucleoside is a locked nucleic acid, or optionally other modifications, and any combination thereof. Also provided are methods of decreasing expression of an ID-I gene in a cell or in a subject to treat an ID-I -related disease. |
| priorityDate |
2007-03-02^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |