http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008133755-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfa9ca4902b71a548899a475d38b2444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abd1720010f18941d443ec59d03892eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cc66341cdee3f44cc006d0bd6ef17e1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 |
| filingDate | 2007-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9600d7e5d64d44d8fef8f476673dc8de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07d936d36085710a831052ccd9a12520 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5288879caf948f9e2633598b8e7af424 |
| publicationDate | 2008-11-06^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008133755-A2 |
| titleOfInvention | Intracellular molecular delivery based on nanostructure injectors |
| abstract | There is disclosed a method and device for the delivery of molecules into individual cells. A device for injecting a biological molecule into a target cell comprises a microscopic tip attached to a mechanical scanning device for positioning the tip relative to the target cell and for moving the tip into the target cell; a nanostructure, such as a carbon nanotube, fixed on an end of the microscopic tip; and a biological molecule attached to the nanotube by a cleavable electrostatic or chemical linker linking the biomolecule to the nanotube, said chemical linker having a chemical linkage which is cleaved in an intracellular environment. The biological molecule may be one or more of proteins, nucleic acids, small molecule drugs, and optical labels, and combinations thereof. Exemplified are multiple walled carbon nanotubes to which a polycyclic aromatic compound is adsorbed, the aromatic compound having a side chain containing a cleavable disulfide linkage and a biotin functionality for coupling to a streptavidin-linked payload. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335491-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013075131-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8257932-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012162546-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012162546-A2 |
| priorityDate | 2007-01-05^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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