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filingDate 2008-08-01^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2009-03-26^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2009038889-A1
titleOfInvention Fhbp- and lpxl1-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
abstract The present invention generally provides methods and compositions for eliciting an immune response against Neisseria spp. bacteria in a subject, using vesicle vaccines made from Neisseria strains have decreased or no detectable expression of a product of LpxL1 gene, and which optionally overexpress fHbp.
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