Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_352e2822a2dfa9795cc7c3fa8ad28086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da83cd9271c3ea560099377018cf3a17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4741ea355d38941d1d95f45188b8162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4204cf99131f78a1ea4608e9df4e7f7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37c13c2877e482bfa569cb7534e58c48 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 |
filingDate |
2008-11-18^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d537311e2507578783ab76f5e34b91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19addd21da76fae9694795525cfb6c1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6f4a9e9b37ada827a92a4399048adeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52e5769490db49b7fd7a4662f70aee9f |
publicationDate |
2009-05-28^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009067031-A1 |
titleOfInvention |
Method for detection and/or assay of lovastatin esterase with use of fluorogenic/chromogenic reagent, lovastatin esterase isolated and/or purified by this method, assembly for detection and/or assay and use of fluorogenic/chromogenic reagent for detection and/or assay of lovastatin esterase |
abstract |
The invention relates to a method for detection and/or assay of the lovastatin esterase enzymatic activity, with use of the fiuorogenic/chromogenic reagent, comprising use of the fiuorogenic/chromogenic reagent of formula II wherein R represents hydrogen or C1-C6-alkyl, R' represents one or two substituents of the ring A, R' represents one or two or three substituents of the ring B. According to a method, the reagent is added to a material of enzymatic activity and the hydrolysis reaction under enzyme action is carried out, followed by detection and/or assay of the liberated coumarin compound of formula III. Also the invention relates to lovastatin esterase isolated and/or purified using this method, an assembly for detection and/or assay of the lovastatin esterase enzymatic activity, an use of the fiuorogenic/chromogenic reagent of formula II for detection and/or assay of the lovastatin esterase enzymatic activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11175204-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9400273-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013044118-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013003168-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111039910-A |
priorityDate |
2007-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |