http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009067031-A1

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filingDate 2008-11-18^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d537311e2507578783ab76f5e34b91
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publicationDate 2009-05-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2009067031-A1
titleOfInvention Method for detection and/or assay of lovastatin esterase with use of fluorogenic/chromogenic reagent, lovastatin esterase isolated and/or purified by this method, assembly for detection and/or assay and use of fluorogenic/chromogenic reagent for detection and/or assay of lovastatin esterase
abstract The invention relates to a method for detection and/or assay of the lovastatin esterase enzymatic activity, with use of the fiuorogenic/chromogenic reagent, comprising use of the fiuorogenic/chromogenic reagent of formula II wherein R represents hydrogen or C1-C6-alkyl, R' represents one or two substituents of the ring A, R' represents one or two or three substituents of the ring B. According to a method, the reagent is added to a material of enzymatic activity and the hydrolysis reaction under enzyme action is carried out, followed by detection and/or assay of the liberated coumarin compound of formula III. Also the invention relates to lovastatin esterase isolated and/or purified using this method, an assembly for detection and/or assay of the lovastatin esterase enzymatic activity, an use of the fiuorogenic/chromogenic reagent of formula II for detection and/or assay of the lovastatin esterase enzymatic activity.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9400273-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013044118-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013003168-A1
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priorityDate 2007-11-19^^<http://www.w3.org/2001/XMLSchema#date>
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