http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010060990-A1

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filingDate 2009-11-27^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b804c61ef68988b739f3a46add563449
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publicationDate 2010-06-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010060990-A1
titleOfInvention Use of p2x7 pathway for assessing the sensitivity of a subject to a cancer treatment
abstract The present invention concerns methods for assessing the sensibility of a subject to an anticancer treatment, for screening compounds which are useful for treating a cancer and for determining the likelihood of a metastatic relapse in a subject. The methods are based on the finding that a non-functional P2X7-elicited NALP3 inflammasome pathway in a subject is indicative of a resistance to treatment. The invention further concerns methods for treating a cancer and for restoring the sensitivity of the subject to a cancer treatment.
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priorityDate 2008-11-27^^<http://www.w3.org/2001/XMLSchema#date>
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