| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58bc273ca61fa077226c6169f6c0f283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96b882006e755dfc56fcabfc5fb019f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28230bf8dea13d8dd45b17939777c283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1246247739d360eaa98ad06eec978d1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39f8863210b1431e61a2f15f017eb1f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62390974becaaa2c6fd15833810ec48c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aab64fec1fedab979fb71b3d823065b4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-416
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
| filingDate |
2009-11-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_526993aa4a30ef5b85e7af95b96f215c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76af47ccdc66dd5059aea4105dcb2cf9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da1953858bcd4b7d5315b169710f1177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_453c7222b10303e8de039669281c5712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c47ffa3242cb0707270d26d55f0588e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229027a45d22c0c3c3c50d1cdaa3e3ec |
| publicationDate |
2010-06-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010068242-A1 |
| titleOfInvention |
Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (pgi2) receptor useful for the treatment of disorders related thereto |
| abstract |
Pyrazole derivatives of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (PAH) and related disorders; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack; angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation; atherosclerosis; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; Crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (SLE); ulcerative colitis; ischemia-reperfusion injury; restenosis; atherosclerosis; acne; type 1 diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (COPD). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3750879-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013050434-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11098034-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299475-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013050437-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013047786-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10689372-B2 |
| priorityDate |
2008-11-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |