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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-535
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535
filingDate 2010-03-17^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_517d1cd9d97deb9c233498264503d13f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9eac55cddf0d8ea8cb7340f442de59f
publicationDate 2010-09-23^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010107485-A1
titleOfInvention E3 ligase inhibitors
abstract The present invention provides, e.g., compounds having the structure of formula (I): The present invention also provides pharmaceutical compositions that include such compounds, and methods for modulating murine double minute 2 protein (Mdm2) E3 ligase activity, particularly the Mdm2-MdmX hetero-complex E3 ligase activity, using such compounds.
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