Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_134a597c1602242a32e87b71dc3495b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6e4a54a61ccf2f9cb4d46d5160eafe6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d744872da14a6a44944859cffa0880a5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F18-2411 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06K9-62 |
filingDate |
2009-06-12^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_326877b5e0844c4c1ed3f0df3bf5ab14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c8da78e52f46289e0b8a8a07d670c7e |
publicationDate |
2010-12-16^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010143941-A1 |
titleOfInvention |
Classification and risk-assignment of childhood acute myeloid leukaemia (aml) by gene expression signatures |
abstract |
The present invention relates to methods of genetic analysis for the classification, diagnosis and prognosis of acute myeloid leukemia (AML). The invention provides a method for producing a classification scheme for childhood acute myeloid leukaemia (AML) comprising the steps of: a) providing a plurality of reference samples, said reference samples comprising cell samples from a plurality of reference subjects suffering from childhood AML, with known class of childhood AML, and optionally known prognosis; b) providing reference profiles by establishing a gene expression profile, matched with parameters for class, and optionally prognosis for each of said reference samples individually; and c) construction of a classifier based upon the gene expression profiles of said reference samples, according to a double-loop cross- validation procedure. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012156515-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109657731-A |
priorityDate |
2009-06-12^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |