| abstract |
The present invention relates to metformin methanesulfonate, to a method for preparing same, to a pharmaceutical composition comprising same, and to a combined formulation comprising same. The metformin methanesulfonate of the present invention has superior stability, enables easy tabletting, has low toxicity, and exhibits excellent AMPKa-activating effects, and thus can be effectively used in treating glycosuria, diabetes, metabolic syndrome, diabetes complications, menstrual irregularities, hypertension, hyperlipidemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovary syndrome, cancer, myalgia, symptoms of muscle cell cytotoxicity, rhabdomyolysis and/or climacterium, etc. |