http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011087562-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cea139ad438b9ce7d33159d45b154c6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_351278d274c5f26116294c7fe9021f0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0279e6dfc354edc3de8bca3ad1bf376d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2f1caebeaf0bbde6db8672ee87463db |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-40043 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8218 |
| filingDate | 2010-11-17^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e03e0df245818af7a577a126c672a7e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4218f80889317f56de323655f981e55e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a690cfc3590243f1449bf25139d1b49 |
| publicationDate | 2011-07-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2011087562-A2 |
| titleOfInvention | An infectious plant viral vector and an artificial bipartite plant viral vector for gene expression or virus-induced gene silencing |
| abstract | We have developed a versatile plant viral vector system based on Alternanthera mosaic virus (AItMV), suitable for infection by agroinfiltration or in vivo T7 transcripts from the same clone; agroinfection is enhanced by coinfiltration of a T7 RNA polymerase construct. Variants adapted for efficient protein expression, or for virus-induced gene silencing (VIGS), are based on a specific amino acid substitution (L88P) in the triple gene block 1 (TGB l) protein affecting RNA silencing suppression. A bipartite delivery system developed for AItMV delivers replicase (RdRp) functions separately from movement and encapsidation (TGB and coat protein, CP) functions by agroinfiltration, resulting in precise recombination of RdRp and TGB-CP constructs in planta . The bipartite delivery system has potential for high throughput protein expression or VIGS with the appropriate TGBl variant, for hosts including Nicotiana benthamiana and Arabidopsis thaliana . Equivalent TGB l substitutions in other potexviruses also reduced RNA silencing suppression, demonstrated with Potato virus X . |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103966256-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103966256-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109234221-A |
| priorityDate | 2009-12-22^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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