abstract |
Provided is a novel compound which has MCH R1 receptor antagonistic activity and is represented by formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the same. (In the formula, the portion AA represented by formula (1) is BB etc., the broken lines indicate whether or not a bond is present, X 1 is O or S, when the broken lines joined to X 2 indicate that a bond is not present, X 2 is N or C(R 3 ), X 4 -X 3 -X 2 is X 4 -O-C(R 4 )(R 4 )-C(R 4 )(R 4 )-X 2 etc., -Y 1 - is a single bond etc., -Y 2 - is a single bond etc., each R 2 is independently a halogen etc., R 3 is hydrogen etc., R 4 is hydrogen etc., D is an alkyl etc., ring B is a cycloalkyl etc., p is an integer of 0 to 4, and q is an integer of 1 to 4. |