Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a30aca1468fa5b8e437c6aeb49bdfb23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3605b50cfe975d0b468d2ce7dcc90d98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b0c3eb80d5cae03ba5067a96f41085b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2011-11-15^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dff05dffa4cb9e7a64bd3786af91c422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cac777142d2ad28330e29a3eff510d79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59d92af23546fe0b3081e3fbadf7e6ce |
publicationDate |
2012-05-24^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012068107-A2 |
titleOfInvention |
Autoantibody to rna-protein complex detected by quantitative pcr |
abstract |
The disclosure provides methods of detecting an autoantibody from a serum sample from a human or animal that is specific for an RNA:protein complex, the method comprising the steps of: (a) obtaining an immunoglobulin-RNA:protein aggregate, wherein said aggregate can comprise a target RNA:protein complex and an RNA:protein complex-specific antibody; (b) isolating the RNA from the immunoglobulin-RNA-protein aggregate; and (c) detecting the isolated RNA by quantitative reverse transcription PCR, whereby detection of the RNA can indicate the presence of the RNA:protein complex-specific antibody in a subject human or animal. One example of the method is configured for the detection of autoantibodies specifically binding to a U3 RNA: protein complex. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112858693-A |
priorityDate |
2010-11-17^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |