| abstract |
Disclosed herein are compositions, systems and methods for delivery of proteins of interest using adeno-associated virus (AAV) vectors. AAV vectors comprising 5' and 3' inverted terminal repeats (ITR), a promoter, a restriction site for insertion of a polynucleotide and a posttranscriptional regulatory element are disclosed. The use of AAV vectors for the expression of neutralizing antibodies is further disclosed. |