| abstract |
Provided are a polypeptide having the functional activity of inhibiting hepatitis B virus x protein (HBx) and a polynucleotide encoding the peptide. Also provided are peptidomimetics of the peptide, including functional fragments and functional variants, as well as the encoding genes thereof. The peptide and peptidomimetics can be used for the prevention and treatment of liver diseases caused by hepatitis B virus infection, including hepatitis, cirrhosis and liver cancer. |