http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014011993-A2

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publicationDate 2014-01-16^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2014011993-A2
titleOfInvention Epitope spreading associated with car t-cells
abstract The present invention relates to compositions and methods for inducing epitope spreading by administering to a mammal an effective amount of a cell genetically modified to express a chimeric antigen receptor (CAR). The invention also relates to identification of antigens and antibodies involved in the epitope spreading associated with CAR T cells.
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