http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014198420-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8637f539b76997d280cbc646d68ca713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2eef30263cb050337a2219a05670c2bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83ae3a3cc80520ef4f6e6cf13ce6b8a1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2014-06-12^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_049789befa43b1c7dffc8083620ffdc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5290ab6a6740beb62c7ad81b3dd26e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f713b84eb2f3e3ed824403a99b55b7df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4ff0f71f9b8d6b7da3d9e45c6bfdd55 |
| publicationDate | 2014-12-18^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2014198420-A1 |
| titleOfInvention | Low molecular weight immune-modulators as adjuvants for specific immunotherapy |
| abstract | The invention relates to a pharmaceutical composition for local modulation of T cell and B cell responses at the site of allergen or antigen presentation, made of one or more preparations comprising one or more antigens or allergens, and a therapeutically effective dose of two or more low molecular weight immune modulators selected from four groups of tolerance- inducing therapeutics comprising inhibitors of complement-mediated functions, inhibitors of tumor necrosis factor receptor 1 (TNFR1) -mediated functions, inhibitors of interleukin 4- and interleukin 13-mediated functions, and therapeutic agents suitable for vitamin D3 supplementation wherein preferably two or more low molecular weight immune modulators and one or more antigens or allergens are coated or adsorbed on or embedded in a matrix, wherein the matrix is selected as to enable sustained release of one or more antigens or allergens and two or more immune modulators for the treatment of T cell-mediated diseases, including allergy, allergic asthma, and autoimmune disease such as type 1 diabetes, rheumatoid arthritis, multiple sclerosis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023035068-A1 |
| priorityDate | 2013-06-13^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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