abstract |
The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-6, and provides an IL-6 binding polypeptide comprising the sequence EEX 3 X 4 AWX 7 EIH X 11 LPNLX 16 X 17 X 18 QX 20 X 21 AFIX 25 X 26 LX 28 X 29 . The present disclosure also relates to the use of such an IL-6 binding polypeptide as a therapeutic, prognostic and/or diagnostic agent. |