http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016118468-A1

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filingDate 2016-01-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_482a9568cb99351677e2df12e3df5491
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publicationDate 2016-07-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2016118468-A1
titleOfInvention Diagnosis of leukocyte-mediated disease and halogen gas exposure
abstract Described are glutathione adducts of fatty aldehydes (FALD-GSH) and methods useful in the detection of FALD-GSH in the identification of pathologies associated with leukocyte-mediated disease conditions, including eosinophil and neutrophil activation. Thus, the present disclosure provides methods of diagnosing a subject as having or being at risk of developing a leukocyte-mediated disease (LMD) comprising (a) detecting the level of glutathione adducts of 2-halofatty aldehydes (FALD-GSH) in a sample; (b) comparing the amount of FALD-GSH with a control or standard reflective of diseased and/or healthy levels of FALD-GSH; and (c) diagnosing the subject as having or being at risk of developing LMD if the level of FALD-GSH in the sample is higher than the control or standard.
priorityDate 2015-01-21^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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