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publicationDate 2016-10-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2016164762-A1
titleOfInvention Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same
abstract The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules encoding low density lipoprotein receptor comprising least one amino acid mutation in the EGF-A domain and at least one or a single amino acid mutation in the intracellular domain.
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