| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-368
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-4926
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-492
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
| filingDate |
2016-07-28^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bed110184381c601b4c53ef6f8bad1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90665ddfb78958a6ce2f908c68462df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_903055bc1d74c6261eaaec9b830db6b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a5e174dcf3655bc20c1c54e53f5c9fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67d8b81c96c22b4c63306ae59024166f |
| publicationDate |
2017-02-02^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017019858-A1 |
| titleOfInvention |
Single nucleotide polymorphic alleles of human dp-2 gene for detection of susceptibility to hair growth inhibition by pgd2 |
| abstract |
DP-2 antagonists reversed PGD 2 -mediated human hair growth inhibition in a dose-dependent manner in vitro by reducing PGD 2 -triggered apoptosis and maintaining proliferation of keratinocytes. Hair follicles from approximately half of the alopecia patients exhibited little susceptibility to PGD 2 's effect in vitro . SNPs in the human DP-2 gene were identified that are associated with hair growth inhibition by PGD 2 . These findings underscore the role of DP-2 in regulating hair growth and indicate that DP-2 can be an effective approach in preventing and/or treating androgenetic alopecia in patients sensitive to PGD 2 . Furthermore, the SNPs identified here can be used to identify patients who will benefit from treatment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112004536-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7049472-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112004536-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021514983-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021202890-A1 |
| priorityDate |
2015-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |