Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c00305de01111733a9d129288f2172ac |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate |
2016-07-28^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda9805ea9cc7365f746493c0d927831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bb06d2ad101e48050ff5ede013aba3c |
publicationDate |
2017-02-09^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2017023671-A1 |
titleOfInvention |
Ezh2 inhibitors and modulation of regulatory t-cell function |
abstract |
Provided herein are methods of treating cancers characterized by a high frequency of one or more suppressive immune cells, comprising administering a therapeutically effective amount of an enhancer of zeste homolog 2 (EZH2) inhibitor. Also provided are combination therapies using an EZH2 inhibitor and a second agent that is an immunomodulator. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3630080-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110944628-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11602529-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786533-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020522687-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3464643-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021035194-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019241742-A1 |
priorityDate |
2015-08-03^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |