abstract |
The present invention relates to aminopyrimidine compounds capable of inhibiting the activity of protein tyrosine kinase, and to preparation and uses thereof. Specifically, disclosed are an aminopyrimidine compound shown in Formula (I), and a pharmaceutically acceptable salt, a stereoisomer, a solvate, a hydrate, a crystal form, a prodrug, or an isotope-variant medicine composition, comprising the compound. The compound in the present invention can be used for treating and/or preventing protein tyrosine kinase related diseases such as cell proliferative diseases, cancers, and immune diseases. |