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publicationDate 2017-09-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017155858-A1
titleOfInvention Nucleic acid sequence identification using solid-phase cyclic single base extension
abstract The present disclosure provides methods, devices and systems for detecting a presence of a nucleic acid molecule having a nucleic acid sequence. Detection of cyclic single base extension can be used to detect a nucleic acid molecule hybridized to a probe and detect a presence of a nucleic acid. The methods disclosed herein can detect a nucleic acid molecule present in a nucleic acid sample at low concentrations and in the presence of background nucleic acids having high sequence similarity.
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