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publicationDate 2019-04-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019067243-A1
titleOfInvention T CELL RECEPTORS RECOGNIZING P53 MUTE
abstract The invention relates to an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated human p53. The present invention also relates to polypeptides and associated proteins, as well as nucleic acids, recombinant expression vectors, host cells, cell populations and associated pharmaceutical compositions. The present invention further provides methods for detecting the presence of cancer in a mammal, and methods for treating or preventing cancer in a mammal.
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