| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-95 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D321-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-18 |
| filingDate |
2018-09-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7de02528820bdd88fa0dbaa611352fa8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4a94bbf1695e8c9deeafd092bb3210f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d694fa1f744fc848cb243d1675c5bbd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6219c5b481cac15fb6ec6f3c97c9c515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43e4d3ec2794ea7c8d8e8adad68e88ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a731a602d785f1857d6f21dcacc34c18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcf7339e66f440c9abe933f3c03b0507
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1fe3c8555895ce833d219487daf047a |
| publicationDate |
2019-04-04^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019067543-A1 |
| titleOfInvention |
COMPOSITIONS AND METHODS OF TREATING CANCER |
| abstract |
The present invention relates to compounds that are capable of penetrating the blood-brain barrier to modulate the activity of EGFR tyrosine kinase. The present invention further provides methods for treating glioblastoma and other cancers involving EGFR. The present invention further provides methods of treating glioblastoma and other EGFR-associated cancers that have been determined to have modified glucose metabolism in the presence of inhibitors. The present invention also relates to methods of administering to a subject an inhibitor of glucose metabolism and a cytoplasmic p53 stabilizer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020190765-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023049312-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022061202-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021127404-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111153891-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111153891-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022076743-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11377451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022066805-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022133345-A1 |
| priorityDate |
2017-09-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |