http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019204733-A1

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publicationDate 2019-10-24^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019204733-A1
titleOfInvention tRNA/pre-miRNA COMPOSITIONS AND METHODS FOR TREATING HEPATOCELLULAR CARCINOMA
abstract Provided are hybrid tRNA/pre-microRNA and tRNA molecules and their use in methods of preventing and treating hepatocellular carcinoma (HCC). In some embodiments, provided are polynucleotides that include a tRNA operably linked to one or more pre-microRNA (pre-miRNA), where the tRNA and/or pre-miRNA are operably linked to one or more inserted RNA molecules that inhibit the growth or proliferation of a hepatocellular carcinoma (HCC) cell.
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