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filingDate 2019-05-23^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_470464a0cdf6234925298423abe1f49e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_585e287e27534a665fefc879799cb6f8
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publicationDate 2019-11-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019224606-A1
titleOfInvention Malaria pre-erythrocytic antigens as a fusion polypeptide and their use in the elicitation of a protective immune response in a host
abstract The invention relates to chimeric Plasmodium antigenic polypeptides derived from pre-erythrocytic (PE) antigens and associated in a fusion polypeptide. In particular, the invention relates to antigenic fusion polypeptides of malaria parasites wherein said antigenic polypeptides exhibit a protective effect, especially that of eliciting a protective immune response in a host against challenge by Plasmodium sporozoites or a sterile response. Such identified antigenic fusion polypeptides may thus constitute active ingredients suitable for the design of a vaccine candidate, in particular a vaccine suitable for a human host.
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