| abstract |
The present invention provides a hard capsule that can be formed by means of a cold gelation process and comprises a hard capsule coating that is enterosoluble. Provided is an enteric hard capsule comprising a coating which contains (a) a first component and a second component or (b) contains a first component and a second component and further contains at least one component from among a third component and a fourth component, wherein: the first component is methylcellulose and/or hydroxypropyl methylcellulose having a viscosity value of 6 mPa·s or higher, the second component is an enterosoluble methacrylic acid copolymer, the third component is a water-insoluble alkyl (meth)acrylate copolymer and/or ethylcellulose, and the fourth component is at least one compound selected from the group consisting of plasticizers that are acceptable pharmaceutically and as food additives and surfactants; and when 100 mass% is the total mass of the first component, the second component, the third component, and the fourth component included in the coating, the ratio of the first component is 30–70 mass%, the ratio of the second component is 30–60 mass%, and the total of the ratios of the first component and the second component is 70 mass% or higher. |