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filingDate 2019-06-17^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2761ec2c1bacb3e67b536bc1ee711a7
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publicationDate 2019-12-26^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019245973-A1
titleOfInvention Adeno-associated virus vector delivery of muscle specific micro-dystrophin to treat muscular dystrophy
abstract The invention provides gene therapy vectors, such as adeno-associated virus (AAV) vectors, expressing a miniaturized human micro-dystrophin gene and method of using these vectors to express micro-dystrophin in skeletal muscle s including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy.
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