| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe2d8a10ec14cd3998ef9c0637e811b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
| filingDate |
2019-08-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0477a37a97b871562a5c4226d4c597cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbd4472dda84c9d53cae1c976960cccb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd40b6d3fc24b78ca28caccd55fcdd4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a744c446fb604a38d7dd53753512c5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2c04305d57d387d668fd018b21c2d4b |
| publicationDate |
2020-02-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020037234-A1 |
| titleOfInvention |
Nucleic acids and nucleic acid analogs for treating, preventing, and disrupting pathological polynucleotide-binding protein inclusions |
| abstract |
Disclosed herein are methods to treat a neurodegenerative disease comprising administering to a subject with a neurodegenerative disease a therapeutically effective amount of a polynucleotide that binds a nucleic acid-binding polypeptide, wherein the nucleic acid-binding polypeptide can aggregate in cells and is associated with a neurodegenerative disease. Also disclosed are methods to inhibit protein aggregation in a cell comprising contacting the cell with a composition comprising a polynucleotide that binds a nucleic acid-binding polypeptide, wherein the nucleic acid-binding polypeptide can aggregate in cells and is associated with a neurodegenerative disease. Additionally disclosed are compositions comprising a polynucleotide that binds a nucleic acid-binding polypeptide, wherein the nucleic acid-binding polypeptide can aggregate in cells and is associated with a neurodegenerative disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021198698-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022120410-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11493519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11340231-B2 |
| priorityDate |
2018-08-16^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |