| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4484f133479fcb9dcd054e09a48b4507 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24322 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-506 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 |
| filingDate |
2020-01-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0919214a99d2eeefb9e54c5c0f9bb87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bccd2c61bd7cb41e7b90accf44d75f22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1332d46487aeff12997c72f9c3330bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57dce33fec3cbcbfcb5b191ee77241eb |
| publicationDate |
2020-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020154635-A1 |
| titleOfInvention |
Fusion constructs for controlling protein function |
| abstract |
Described herein are engineered fusion proteins comprising a variant protease (e.g., an HCV NS3 protease) fused to a polypeptide of interest and a cognate protease cleavage site. The cleavability of the cognate protease cleavage site enables the controllability of one or more functions of the polypeptide of interest. Additionally disclosed are methods for generating engineered fusion proteins as well as their therapeutic use. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4041316-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112225783-A |
| priorityDate |
2019-01-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |