| abstract |
The present invention pertains to a ligand-drug conjugate comprising: a ligand; a linker which is covalently linked to the ligand and includes a tris structure represented by a specific structural formula; and active agents covalently linked to the linker. In the ligand-drug conjugate, the active agents are linked by the tris structure of the linker, and thus a greater number of active agents can be connected through a single linker. Accordingly, a greater number of active agents per antibody binding can be delivered to target cells, and drugs and/or toxins can reliably reach the target cells and effectively exhibit medicinal effects. |