http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020231205-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b35defdaf2eb371391cf1b2e32fb71a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-599 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2531-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0646 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
| filingDate | 2020-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fafbd2feb5a18db6ef48493a6f28d7b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe57b3428638b17cd59e4a5368cff820 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ed62e6dd8a08d10567ab5252a0f84e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ac696e7eba3d106723d894383d66f42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85f426811777d96c2b8d1bb599dba999 |
| publicationDate | 2020-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2020231205-A1 |
| titleOfInvention | Composition for culturing natural killer cells, and method using same |
| abstract | The present invention pertains to: a composition for culturing natural killer cells; a kit; and a method using same. According to a composition for culturing natural killer cells according to an aspect, and a method for culturing natural killer cells using same, when culturing natural killer cells from peripheral blood mononuclear cells, the natural killer cells can be proliferated in large quantities, and the activation or inhibition of the natural killer cells, as well as the expansion of the natural killer cells, can be promoted by culturing the natural killer cells in a medium containing a composition for culturing natural killer cells, the composition containing magnetic beads having an activating receptor ligand, an inhibitory receptor ligand, a costimulatory receptor ligand, a cytokine, a cytokine receptor, an immune checkpoint ligand, a blocking antibody, or a combination thereof attached to at least one side. Therefore, the natural killer cells thus cultured can be advantageously used as an immune cell therapeutic agent. Furthermore, the magnetic beads can be easily removed from the medium, thus providing convenience and cost-effectiveness, and the present invention uses safe magnetic beads, thus having excellent clinical safety. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023089561-A1 |
| priorityDate | 2019-05-15^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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