| abstract |
The purpose of the present invention is to provide: a method for preparing urothelial cells that are applicable to the treatment of urinary system diseases, in particular diseases caused by damaged urothelial cells, and diseases due to the loss or dysfunction of urothelial cells; urothelial cells prepared by this method; and a medium for inducing (preparing) urothelial cells. In the present invention, urothelial cells prepared by this method for inducing urothelial cells are applicable for the treatment of urinary system diseases, the method including a step for introducing at least one selected from the group consisting of FOXA1 (Forkhead box A1) gene or an expression product thereof, TP63 (tumor protein P63) gene or an expression product thereof, MYCL (L-Myc) gene or an expression product thereof, and KLF4 (Kruppel-like factor 4) gene or an expression product thereof into mammalian somatic cells as an exogenous factor. |