http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021046233-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4aba5130b481ea5be1710d495eac3cad
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
filingDate 2020-09-03^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f75a53ee735a1411b8ce3aa179afbb5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d42ff08ebb9aafc48a00d34a7d17af75
publicationDate 2021-03-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021046233-A1
titleOfInvention Chelate-containing psma inhibitors
abstract Provided herein are PMSA-binding molecules comprising a albumin-binding moiety and a chelating agent optionally chelating a therapeutic radioisotope or a PET-active, SPECT-active, or MR I -active radioisotope. The compound of Formula (II*) (and its therapeutically acceptable salt) is representative. Also provided are compositions including a compound of the disclosure together with a pharmaceutically acceptable carrier, methods for imaging prostate cancer cells with radioisotope-chelated compounds of the disclosure, and methods of synthesizing the compounds.
priorityDate 2019-09-03^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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