| abstract |
The treatment according to the invention provides the use of at least one peptide having the general Formula X-(Xaa)nK*TTK*X'aa-(Xaa)m-Z for a non-therapeutic cosmetic treatment of keratinous tissues of the skin and of its appendages. In the Formula, K* is selected from lysine, hydroxylysine, ornithine, diaminobutyric acid or diaminopropionic acid or their formylated, acetylated, trifluoroacetylated, methanesulfonylaed or succinylated derivatives, both K* being identical or different; (Xaa)n and (Xaa)m correspond independently of one another to a sequence of n or m amino acids Xaa selected independently of one another from Gly, Ala, Pro, Val, Leu, Ile and Phe, with n and m being integers which can be equal or different and comprised between 0 and 5; X'aa is selected from threonine and serine; At the N-terminal end X is selected from H, -CO-R1, -SO2-R1 or a biotinoyle group; At the C-terminal end Z is selected from OH, OR1, NH2, NHR1 or NR1R2; and R 1 and R2 being, independently of one another, selected from an alkyl, aryl, aralkyl, alkylaryl, alkoxy, saccharide and aryloxy group, which can be linear, branched, cyclic, polycyclic, unsaturated, hydroxylated, carbonylated, phosphorylated and/or sulfurated, said group having from 1 to 24 carbon atoms and the possibility of having in its backbone one or more O, S and/or N heteroatoms. A preferred peptide is the Pal-KTTKS. |