abstract |
The present invention relates to the field of DNA virus infection, in particular to therapy and diagnosis of a DNA virus infection in a subject. Specifically, the present invention relates to the use of arsenic trioxide (As2O3) for treating or preventing an adenovirus infection or hepatitis B virus (HBV) infection in a subject. Furthermore, the present invention relates to a method of detecting an adenovirus infection or HBV infection based on detecting SUMOylation of adenoviral E2A protein or HBV core (HBc) protein, respectively, in a patient sample. |