http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021228967-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8472b54b2e15439e8ed79e00d0af01b0
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
filingDate 2021-05-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a12b4c0ac098f45c393a513b93d9766f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_843c0cc0872d59fb4dafce4bb7f4119c
publicationDate 2021-11-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021228967-A1
titleOfInvention ACTIVE AND ORTHOGONAL HYBRID PYRROLYSYL tRNA
abstract The present invention relates to a hybrid pyrrolysyl tRNA (PylT), which is highly orthogonal and active. The invention furthermore provides a complex comprising a hybrid pyrrolysyl tRNA (PylT) and a pyrrolysyl-tRNA-synthetase (PylRS) (PylT/PylRS), as well as a pair of PylT/PylRS complexes, which are mutually orthogonal and active in the same system. The present invention allows for incorporation of at least one, such as two distinct, non-canonical amino acids (ncAA) into a protein.
priorityDate 2020-05-13^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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