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publicationDate 2022-07-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2022159436-A1
titleOfInvention Inhibitors of dyrk and pim
abstract Provided is a compound, including a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein W is a direct bond or an optionally substituted C, and if W is a direct bond, then X 1 , X 2 , X 3 , and X 4 are each independently H, OH, or an electrophile, and optionally one pair selected from X 1 and X 2 , X 2 and X 3 , and X 3 and X 4 forms a five-membered ring including one or more heteroatom, wherein the one or more heteroatom is selected from O, N, and S, and the five-membered ring is optionally substituted with a =C, an =S, or an electrophile, and Y 1 , Y 2 , Y 3 , Y 4 and Y 5 are each independently selected from H, CH 3 , OH, O-CH 3 , and NO 2 , and an electrophile, and optionally Y 2 and Y 3 form a five-membered ring including one or more heteroatom, wherein the one or more heteroatom is selected from O, N, and S, and the five-membered ring is optionally substituted with a =C, =S, or an electrophile.
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226397203
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_002006
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7175
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCG3V7R4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP21251
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1859
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226394420
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395486
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395485
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6PI52
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID477207304
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO97341
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4L7N3
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID768121

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