| abstract |
The present invention relates to a novel medical use of glucagon, and other compounds with glucagon activity, as vasodilators, to assist in the delivery of therapeutic agents or in the operation of sensor devices which determine the level of analytes in the blood. In particular, the compound is administered in temporal coordination with the active agent and/or in conjunction with determination of the analyte by a bodily sensor, and at a site which is in the vicinity of the site of administration of the active agent and/or of the site(s) of sensing of the analyte by the bodily sensor. This includes in particular the delivery of insulin in the treatment of diabetes, and the determination of blood glucose levels by glucose sensors. Also provided herein are integrated systems for performing the medical uses and therapies. |