| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2b691adfbe996405b793466d1b87a5c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D63-082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-491 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D63-08 |
| filingDate |
1979-05-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f86f61b94fc13800109ea0bcfd30a981
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7042106a37ca3cab0acf3425ae35b9d9 |
| publicationDate |
1979-12-27^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-7901120-A1 |
| titleOfInvention |
Filtration apparatus for separating blood cell-containing liquid suspensions |
| abstract |
A filtration device (10) for effecting separation of a blood cell-free liquid filtrate from a blood cell-containing liquid suspension in continuous laminar flow therethrough, employing a microporous filtration membrane (32). The filtration flow channels (130) along the surface of the upstream side of the membrane (32) wall are provided with a width across the membrane wall surface which gradually and uniformly increases from the inlet end (22) to the outlet end (24) of the flow channel, whereby the membrane wall shear rate of the suspension in laminar flow through the flow channel (130) will gradually and uniformly vary along the length of the flow channel (130) from a maximum value at its inlet end (22) to a minimum value at its outlet end (24). Such variation in shear rate corresponds with the variation in the transmembrane pressure conditions along the length of the flow channel (130) so as to enable better control of the filtration operating conditions to ensure optimal filtration rates per area of membrane (32) without damage to the blood cells. Useful applications of the device (10) include the separation of plasma from whole blood in a continuous flow plasmapheresis procedure, and the removal of cryoprotective agents from previously frozen, thawed preparations of blood cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6387290-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2343853-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9700121-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108949565-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5922210-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4432628-B4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0081101-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4939096-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2513896-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4631130-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0044958-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2542620-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0263978-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2529084-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2576805-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2343853-A |
| priorityDate |
1978-05-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |