http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9307881-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d3a63854c7a1afe23086eebce835f46 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate | 1992-10-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95ebf9e09350b2830f8fa81c8bc85e0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c0f7b633c55785889d7c9f4384418e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_762c51369003c937e14ac66976e3bbfa |
| publicationDate | 1993-04-29^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9307881-A1 |
| titleOfInvention | Inhibition of viruses by the administration of homopolyribonucleotides and/or duplex polymers |
| abstract | A series of polyribonucleotides containing methyl and/or sulphur substitutions such as poly(1-methyl-6-thioinosinic acid) also [poly(m1s6I)], poly(1-methyl-6-thioguanylic) acid [poly(m1s6G)], and poly(6-thioguanylic acid) complexed with polycytidylic acid [poly(s6G)-poly(C)] are useful in treating human cells infected with AIDS viruses or viral opportunistic pathogens by inhibiting the virus from developing or spreading to unaffected cells. Poly(m1s6I), poly(m1s6G), and poly(s6G)-poly(C) may be administered orally, parenterally or transdermally per se or in the form of a pharmaceutically acceptable salt. As regarding the AIDS virus, these agents function in one or more ways as inhibitors of the viral reverse transcriptase necessary for viral replication, and/or also block the formation of syncytia (giant cells) which are characteristic of HIV infection and facilitate the transmission of the virus to uninfected cells. |
| priorityDate | 1991-10-16^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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